In the action kardiovakular disease, the analysis of a stent is a astounding thing. Once begin stant and balloons, afresh accessible anaplasty to affected the absorption of claret argosy through operations by canyon can be avoided. Around 1997 Percutaneous coronary action (PCI) with stent and the airship began to be acclimated broadly by the cardiologist in the world. However, afresh additionally started to acquisition the weaknesses of DES, which account claret to array or backward stent thrombosis. Stent occlusion usually occurs in the aboriginal ages afterwards stent. However, backward stent occlusion showed occlusion occurs afterwards months or alike several years afterwards the stent. Afresh a new technology developed to affected weaknesses DES, the drug-eluting baloon or DEB. In the DEB, the basal abstraction with the absolution of the biologic DES, it's aloof not use polymers DEB. As acclimated pemmbawa drug-free cast polymer (polymer-matrix carrier biologic fee) so there is no metal or polymer as a annoyance is larboard afterwards the procedure. Unique cast technology allows the biologic is delivered anon to the bane so that the administration pbat absorption becomes effective. Recent studies DEB showed able results. One of these studies PEPCAD (Paxlitaxel-Eluting PTCA-Ballon Catheter in Coronary Avenue Disease). Two multicenter studies of PEPCAD I and II PEPCAD conducted by advisers from the Clinical Research Institute, Center for Cardiovascular Ache in Germany, has anniversary affairs dipresenntasikan TCT (Transcatheter Cardiovascular Therapeutics) in Whasington DC, United States, and in October 2007. I PEPCAD abstraction led by Dr. Martin Unverdorben from Rotenburg, Germany. There were 120 patients with absorption of baby claret argosy and advised with DEB. Afterwards 6 months, alone 5.5% of patients accomplished restenosis and above adverse cardiac amount contest (MACE) is alone 6.1%, compared to the use of DES, which was appear beforehand ie 31.2% 18.9% restenosis and MACE.
Functions abide for the analysis of coronary affection avenue to widen the channels (blood vessels) so that claret can breeze calmly again. DEB method, it can widen claret argosy alternate with the advice of a airship and the biologic (paclitaxel) independent in it, this biologic will be captivated bound and anticipate the actualization of new crust.
PEPCAD Abstraction II, is the aboriginal abstraction to anon analyze DES and DEB instent in patients with restenosis (ISR). There were 131 patients who were included in the abstraction for added than 6 months. The abstraction shows, alone 3.7% of patients who accomplished restenosis and MACE 4.8% in those who were advised with DEB. Analyze this with 20.8% 22.0% restenosis and MACE in DES group.
The abstraction connected until PEPCAD still PEPCAD IV, the abstraction application the DEB in patients with diabetes. This abstraction is demography abode in Malaysia and Thailand. There were 128 patients complex and the new abstraction began in July 2007 then. The plan of abstraction aeon will aftermost up to 3 years. From the after-effects of a abstraction of the DEB, analysis for coronary affection ache are 'spot treatment', acceptation all patients who accept accustomed analysis should accomplish affairs changes or behavior to abstain absorption afresh elsewhere. One of them is to stop smoking, because of coronary affection ache patients beneath the age of 40 years about all of them are smokers. Conclusion according to the experts: that the DEB is actual absolute for coronary avenue penyakt overcome. "Excellence DEB is akin biologic absolution after polymer. Minimal biologic exposure, after the charge for bifold antiplatelet therapy,"
